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Article

Striatal dopamine output is compromised within +/- BDNF mice.

Synapse (New York, N.Y.) - 1 Feb 2002

Dluzen Dean E, Anderson Linda I, McDermott Janet L, Kucera Jan, Walro Jon M

Abstract excerpt

We reported previously that mice lacking one brain-derived neurotrophic factor (BDNF) allele demonstrate elevated striatal dopamine (DA) concentrations but impaired behavioral responses involving the nigrostriatal dopaminergic (NSDA) system. To test the hypothesis that these elevated striatal DA concentrations are associated with perturbed NSDA functioning, we compared striatal DA output between heterozygous...

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Source

Identifiers

PMID: 11754489
DOI: 10.1002/syn.10027

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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