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Article

A major single nucleotide polymorphism of the PDLIM5 gene associated with recurrent major depressive disorder.

Journal of psychiatry & neuroscience : JPN - 1 Jan 2008

Liu Zhongchun, Liu Wanhong, Xiao Zheman, Wang Gaohua, Yin Shijin, Zhu Fan, Wang Huiling, Cheng Jin, Wang Xiaoping, He Xiaohua, Li Wenxin

Abstract excerpt

OBJECTIVE: The PDLIM5 gene is known to interact specifically with the N-type calcium channel alpha-1B subunit and protein kinase C epsilon and is critical for rapid, efficient potentiation of the calcium channel activation by protein kinase C in neurons. Increasing amounts of data suggested that PDLIM5 might be involved in the pathophysiology of major depressive disorder (MDD). The aim of this study was to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18197271
PMCID: PMC2186365

Genes

PDLIM5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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