Article
A major single nucleotide polymorphism of the PDLIM5 gene associated with recurrent major depressive disorder.
Journal of psychiatry & neuroscience : JPN - 1 Jan 2008
Liu Zhongchun, Liu Wanhong, Xiao Zheman, Wang Gaohua, Yin Shijin, Zhu Fan, Wang Huiling, Cheng Jin, Wang Xiaoping, He Xiaohua, Li Wenxin
Abstract excerpt
OBJECTIVE: The PDLIM5 gene is known to interact specifically with the N-type calcium channel alpha-1B subunit and protein kinase C epsilon and is critical for rapid, efficient potentiation of the calcium channel activation by protein kinase C in neurons. Increasing amounts of data suggested that...
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