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Article

Promotion of BRCA1-associated triple-negative breast cancer by ovarian hormones.

Current opinion in obstetrics & gynecology - 1 Feb 2008

Lee Eva Y-H P

Abstract excerpt

PURPOSE OF REVIEW: Mammary epithelial proliferation is controlled by the ovarian hormones estrogen and progesterone. Although BRCA1 (breast cancer 1, early onset) is ubiquitously expressed, women with BRCA1 mutations have a propensity to develop tumors in tissues sensitive to ovarian hormone. An understanding of the tissue-specific function of the BRCA1-encoded protein (BRCA1) provides additional insight that may...

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Share to BRCA1 Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Estrogen Receptor alpha

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Share to Receptors, Progesterone

Source

Identifiers

PMID: 18197009
DOI: 10.1097/GCO.0b013e3282f42237

Genes

BRCA1
BARD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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