Article
Genotypes, haplotypes and diplotypes of XPC and risk of bladder cancer.
Carcinogenesis - 1 Mar 2007
Zhu Yimin, Lai Maode, Yang Hushan, Lin Jie, Huang Maosheng, Grossman H Barton, Dinney Colin P, Wu Xifeng
Abstract excerpt
Xeroderma pigmentosum complementation group C (XPC) is responsible for DNA damage recognition in the initial steps of the nucleotide excision repair pathway. Genetic variations in the XPC gene may be associated with impaired protein function and increased risk for bladder cancer. To elucidate the roles of common polymorphisms of XPC in the etiology of bladder cancer, we conducted a hospital-based case-control...
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