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Article

Pvt1-encoded microRNAs in oncogenesis.

Retrovirology - 14 Jan 2008

Beck-Engeser Gabriele B, Lum Amy M, Huppi Konrad, Caplen Natasha J, Wang Bruce B, Wabl Matthias

Abstract excerpt

BACKGROUND: The functional significance of the Pvt1 locus in the oncogenesis of Burkitt's lymphoma and plasmacytomas has remained a puzzle. In these tumors, Pvt1 is the site of reciprocal translocations to immunoglobulin loci. Although the locus encodes a number of alternative transcripts, no protein or regulatory RNA products were found. The recent identification of non-coding microRNAs encoded within the PVT1...

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Share to Virus Integration
Share to Genes, myc
Share to Lymphoma, T-Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred BALB C

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Source

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Identifiers

PMID: 18194563
DOI: 10.1186/1742-4690-5-4
PMCID: PMC2257975

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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