Article
Mutations in latent membrane protein 1 of Epstein-Barr virus are associated with increased risk of posttransplant lymphoproliferative disorder in children.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 May 2023
Martinez Olivia M, Krams Sheri M, Robien Mark A, Lapasaran Mary G, Arvedson Matthew P, Reitsma Andrea, Balachandran Yarl, Harris-Arnold Aleishia, Weinberg Kenneth, Boyd Scott D, Armstrong Brian, Trickey Amber, Twist Clare J, Gratzinger Dita, Tan Brent, Brown Merideth, Chin Clifford, Desai Dev M, Fishbein Thomas M, Mazariegos George V, Tekin Akin, Venick Robert S, Bernstein Daniel, Esquivel Carlos O
Abstract excerpt
Epstein-Barr virus (EBV)-positive posttransplant lymphoproliferative disorder (PTLD) results in significant morbidity and mortality in pediatric transplant recipients. Identifying individuals at an increased risk of EBV-positive PTLD could influence clinical management of immunosuppression and other therapies, improving posttransplant outcomes. A 7-center prospective, observational clinical trial of 872 pediatric...
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