Article
Expression of the vault RNA protects cells from undergoing apoptosis.
Nature communications - 8 May 2015
Amort Melanie, Nachbauer Birgit, Tuzlak Selma, Kieser Arnd, Schepers Aloys, Villunger Andreas, Polacek Norbert
Abstract excerpt
Non-protein-coding RNAs are a functionally versatile class of transcripts exerting their biological roles on the RNA level. Recently, we demonstrated that the vault complex-associated RNAs (vtRNAs) are significantly upregulated in Epstein-Barr virus (EBV)-infected human B cells. Very little is known about the function(s) of the vtRNAs or the vault complex. Here, we individually express latent EBV-encoded proteins...
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