Article
Heterozygous embryonic stem cell lines derived from nonhuman primate parthenotes.
Stem cells (Dayton, Ohio) - 1 Mar 2008
Dighe Vikas, Clepper Lisa, Pedersen Darlene, Byrne James, Ferguson Betsy, Gokhale Sumita, Penedo M Cecilia T, Wolf Don, Mitalipov Shoukhrat
Abstract excerpt
Monoparental parthenotes represent a potential source of histocompatible stem cells that should be isogenic with the oocyte donor and therefore suitable for use in cell or tissue replacement therapy. We generated five rhesus monkey parthenogenetic embryonic stem cell (PESC) lines with stable, diploid female karyotypes that were morphologically indistinguishable from biparental controls, expressed key pluripotent...
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