Article
A highly homozygous and parthenogenetic human embryonic stem cell line derived from a one-pronuclear oocyte following in vitro fertilization procedure.
Cell research - 1 Dec 2007
Lin Ge, OuYang Qi, Zhou Xiaoying, Gu Yifan, Yuan Ding, Li Wen, Liu Gang, Liu Tiancheng, Lu Guangxiu
Abstract excerpt
Homozygous human embryonic stem cells (hESCs) are thought to be better cell sources for hESC banking because their human leukocyte antigen (HLA) haplotype would strongly increase the degree of matching for certain populations with relatively smaller cohorts of cell lines. Homozygous hESCs can be generated from parthenogenetic embryos, but only heterozygous hESCs have been established using the current strategy to...
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