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Article

Recombination signatures distinguish embryonic stem cells derived by parthenogenesis and somatic cell nuclear transfer.

Cell stem cell - 13 Sept 2007

Kim Kitai, Ng Kitwa, Rugg-Gunn Peter J, Shieh Jae-Hung, Kirak Oktay, Jaenisch Rudolf, Wakayama Teruhiko, Moore Malcolm A, Pedersen Roger A, Daley George Q

Abstract excerpt

Parthenogenesis and somatic cell nuclear transfer (SCNT) are two methods for deriving embryonic stem (ES) cells that are genetically matched to the oocyte donor or somatic cell donor, respectively. Using genome-wide single nucleotide polymorphism (SNP) analysis, we demonstrate distinct signatures of genetic recombination that distinguish parthenogenetic ES cells from those generated by SCNT. We applied SNP...

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Identifiers

PMID: 18371368
DOI: 10.1016/j.stem.2007.07.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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