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Article

Curcumin inhibits aggregation of alpha-synuclein.

Acta neuropathologica - 1 Apr 2008

Pandey Neeraj, Strider Jeffrey, Nolan William C, Yan Sherry X, Galvin James E

Abstract excerpt

Aggregation of amyloid-beta protein (Abeta) is a key pathogenic event in Alzheimer's disease (AD). Curcumin, a constituent of the Indian spice Turmeric is structurally similar to Congo Red and has been demonstrated to bind Abeta amyloid and prevent further oligomerization of Abeta monomers onto growing amyloid beta-sheets. Reasoning that oligomerization kinetics and mechanism of amyloid formation are similar in...

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PMID: 18189141
DOI: 10.1007/s00401-007-0332-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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