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Article

Curcumin modulates cell death and is protective in Huntington's disease model.

Scientific reports - 5 Jan 2016

Chongtham Anjalika, Agrawal Namita

Abstract excerpt

Huntington's disease (HD) is a progressive, dominantly inherited neurological disorder caused by an abnormal expansion of polyglutamine (polyQ) repeat within the Huntingtin (Htt) protein with no disease modifying treatments. In a Drosophila model of HD, expression of mutant Huntingtin (Htt) protein with expanded polyQ leads to formation of inclusion bodies (IBs), increase in cellular toxicity, progression of...

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Identifiers

PMID: 26728250
DOI: 10.1038/srep18736
PMCID: PMC4700531

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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