Article
Lsr2 of Mycobacterium tuberculosis is a DNA-bridging protein.
Nucleic acids research - 1 Apr 2008
Chen Jeffrey M, Ren Huiping, Shaw James E, Wang Yu Jing, Li Ming, Leung Andrea S, Tran Vanessa, Berbenetz Nicolas M, Kocíncová Dana, Yip Christopher M, Reyrat Jean-Marc, Liu Jun
Abstract excerpt
Lsr2 is a small, basic protein present in Mycobacterium and related actinomycetes. Recent studies suggest that Lsr2 is a regulatory protein involved in multiple cellular processes including cell wall biosynthesis and antibiotic resistance. However, the underlying molecular mechanisms remain unknown. In this article, we performed biochemical studies of Lsr2-DNA interactions and structure-function analysis of Lsr2....
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