Article
EXOG, a novel paralog of Endonuclease G in higher eukaryotes.
Nucleic acids research - 1 Mar 2008
Cymerman Iwona A, Chung Inn, Beckmann Benedikt M, Bujnicki Janusz M, Meiss Gregor
Abstract excerpt
Evolutionary conserved mitochondrial nucleases are involved in programmed cell death and normal cell proliferation in lower and higher eukaryotes. The endo/exonuclease Nuc1p, also termed 'yeast Endonuclease G (EndoG)', is a member of this class of enzymes that differs from mammalian homologs by the presence of a 5'-3' exonuclease activity in addition to its broad spectrum endonuclease activity. However, this...
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