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Article

Resequencing Epithelial Sodium Channel Genes Identifies Rare Variants Associated With Blood Pressure Salt-Sensitivity: The GenSalt Study.

American journal of hypertension - 12 Jan 2018

Gu Xiaoying, Gu Dongfeng, He Jiang, Rao Dabeeru C, Hixson James E, Chen Jichun, Li Jianxin, Huang Jianfeng, Wu Xigui, Rice Treva K, Shimmin Lawrence C, Kelly Tanika N

Abstract excerpt

BACKGROUND: A resequencing study of renal epithelial sodium channel (ENaC) genes was conducted to identify rare variants associated with blood pressure (BP) salt-sensitivity. METHODS: The Genetic Epidemiology Network of Salt-Sensitivity (GenSalt) study was conducted among 1,906 participants who underwent a 7-day low-sodium followed by a 7-day high-sodium feeding-study. The 300 most salt-sensitive and 300 most...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Sodium Chloride, Dietary

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Identifiers

PMID: 29036630
DOI: 10.1093/ajh/hpx169
PMCID: PMC5861537

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Source receipt: pubmed, retrieved 7 Sept 2026.

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