A vector driving the expression of foreign cDNAs in the MHC class II-positive cells of transgenic mice.

doi:10.1016/0022-1759(93)90370-m

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Article

A vector driving the expression of foreign cDNAs in the MHC class II-positive cells of transgenic mice.

Journal of immunological methods - 3 Dec 1993

Kouskoff V, Fehling H J, Lemeur M, Benoist C, Mathis D

Abstract excerpt

We describe a plasmid vector that drives the expression of foreign cDNAs in transgenic mice, according to the dictates of an MHC class II gene promoter. Using this vector, we have often obtained mRNA and protein synthesis with a tissue and cell-type specificity indistinguishable from that of the...

Topics

Animals
Antibody Formation
DNA, Complementary
Epitopes
Gene Expression
Genes, MHC Class II
Genetic Vectors
Histocompatibility Antigens Class II
Mice
Mice, Transgenic
Mutation
Plasmids
Promoter Regions, Genetic
Rabbits

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