Article
Prostate cancer in male BRCA1 and BRCA2 mutation carriers has a more aggressive phenotype.
British journal of cancer - 29 Jan 2008
Mitra A, Fisher C, Foster C S, Jameson C, Barbachanno Y, Bartlett J, Bancroft E, Doherty R, Kote-Jarai Z, Peock S, Easton D, Eeles R
Abstract excerpt
There is a high and rising prevalence of prostate cancer (PRCA) within the male population of the United Kingdom. Although the relative risk of PRCA is higher in male BRCA2 and BRCA1 mutation carriers, the histological characteristics of this malignancy in these groups have not been clearly defined. We present the histopathological findings in the first UK series of BRCA1 and BRCA2 mutation carriers with PRCA....
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