Article
Clinical features and management of BRCA1 and BRCA2-associated prostate cancer.
Frontiers in bioscience (Elite edition) - 1 Jan 2014
Alanee Shaheen R, Glogowski Emily A, Schrader Kasmintan A, Eastham James A, Offit Kenneth
Abstract excerpt
It is thought that over forty percent of an individual's risk of developing prostate cancer (PCa) is related to familial and genetic factors. Although multiple genes have been implicated in the development of PCa, few confer as high a risk as mutations in the genes associated with early-onset breast cancer (BRCA1 and BRCA2). Not only do mutations in BRCA genes increase the risk of PCa, but they have also been...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.