Article
Enhanced progression of human prostate cancer PC3 cells induced by the microenvironment of the seminal vesicle.
British journal of cancer - 29 Jan 2008
Kumano M, Miyake H, Kurahashi T, Yamanaka K, Fujisawa M
Abstract excerpt
The objective of this study was to characterise the mechanism mediating the prostate cancer progression induced by the microenvironment of seminal vesicle (SV). The invasive potential of PC3 cells significantly increased after treatment with extract from SV of NOD/SCID mouse. Among several growth factors and cytokines that were present in the SV extract, transforming growth factor-beta(1) (TGF-beta(1))...
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