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Article

Ets-1 triggers and orchestrates the malignant phenotype of mammary cancer cells within their matrix environment.

Journal of cellular physiology - 1 Jun 2008

Furlan Alessandro, Vercamer Chantal, Desbiens Xavier, Pourtier Albin

Abstract excerpt

Acquisition of invasive characteristics is a hallmark of breast carcinoma progression. During this phenomenon, Ets-1 transcription factor overexpression is induced and associated with breast cancer invasiveness, and poor prognosis. We hypothesized that Ets-1 transcription factor could be the orchestrator of a genetic program inducing the expression of genes necessary for cell motility, as postulated by the tumor...

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Identifiers

PMID: 18181172
DOI: 10.1002/jcp.21360

Genes

HGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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