Article
Interleukin-6 -174 genotype, periodontal disease and adverse pregnancy outcomes: a pilot study.
Journal of clinical immunology - 1 May 2008
Dashash M, Nugent J, Baker P, Tansinda D, Blinkhorn F
Abstract excerpt
This study was undertaken to investigate whether maternal periodontal disease and variant genotypes of IL-6 gene are associated with adverse pregnancy outcomes. A total of 145 pregnant women were recruited from St Mary's Hospital, Manchester, UK. Bleeding on probing (BOP) and pocket depth indices were recorded on all teeth. Amplification refractory mutation system-polymerase chain reaction was used for -174 IL-6...
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