Article
Interleukin-6 genotype and risk for cerebral palsy in term and near-term infants.
Annals of neurology - 1 Nov 2009
Wu Yvonne W, Croen Lisa A, Torres Anthony R, Van De Water Judy, Grether Judith K, Hsu Nathaniel N
Abstract excerpt
OBJECTIVE: Chorioamnionitis is associated with increased risk for cerebral palsy (CP) in term infants. A functional polymorphism in the interleukin-6 (IL-6) gene has been implicated in newborn brain injury. We studied whether the IL-6 -174 G/C polymorphism confers increased risk for CP in term infants. METHODS: This population-based case-control study included 334,333 live-born infants born at >or=36 weeks...
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