Article
[The significance of -174G/C polymorphism of the gene coding for interleukin-6 in neonatal infections].
Ginekologia polska - 1 Feb 2005
Wojsyk-Banaszak Irena, Seremak-Mrozikiewicz Agnieszka, Szczapa Jerzy, Drews Krzysztof, Zandecka-Dziubak Joanna, Mrozikiewicz Przemysław M
Abstract excerpt
OBJECTIVE: Interleukin-6 (IL-6) is a specific marker of early onset infections in the newborns. In recent years it has been suggested that in regulations of IL-6 activity could play a role the genetic polymorphism (-174G/C) in the promoter region of the gene coding for IL-6. The aim of our study was to analyse the frequency of -174G/C polymorphism of interleukin-6 gene as a genomic marker for individuals at an...
Topics
- Amniotic Fluid
- Case-Control Studies
- Cytosine
- Female
- Gene Frequency
- Guanine
- Humans
- Infant, Newborn
- Interleukin-6
- Male
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Polymorphism, Single Nucleotide
- Pregnancy