Article
Polymorphisms in von Willebrand factor gene promoter influence the glucocorticoid-induced increase in von Willebrand factor: the lesson learned from Cushing syndrome.
British journal of haematology - 1 Jan 2008
Casonato Alessandra, Daidone Viviana, Sartorello Francesca, Albiger Nora, Romualdi Chiara, Mantero Franco, Pagnan Antonio, Scaroni Carla
Abstract excerpt
Cushing syndrome (CS) features high-glucocorticoid secretion and an associated hypercoagulable state often involving an increase in von Willebrand factor (VWF). To identify any influence of VWF promoter on glucocorticoid haemostatic effects, four polymorphic positions (-3267, -2708, -2659 and -25...
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