Article
Glucocorticoid receptor gene polymorphisms in hereditary angioedema with C1-inhibitor deficiency.
Orphanet journal of rare diseases - 10 Jan 2017
Zotter Zsuzsanna, Nagy Zsolt, Patócs Attila, Csuka Dorottya, Veszeli Nóra, Kőhalmi Kinga Viktória, Farkas Henriette
Abstract excerpt
BACKGROUND: Hereditary angioedema caused by C1-inhibitor deficiency (C1-INH-HAE) is a rare, autosomal dominant disorder. C1-INH-HAE is characterized by edema-formation, which may occur in response to stress. The individual's response to stress stimuli is partly genetically determined. Activation of the hypothalamic-pituitary-adrenal axis results in the release of cortisol. In turn, the secreted gluco- and...
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