Article
Effect of glucocorticoids on von Willebrand factor levels and its correlation with von Willebrand factor gene promoter polymorphism.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Sept 2012
Chopra Anita, Kumar Rajive, Kishore Kamal, Tandon Nikhil, Yusuf Tanveer, Kumar Suman, Mishra Pravas, Saxena Renu
Abstract excerpt
von Willebrand factor (vWF) gene promoter polymorphism at nucleotide positions -2659 and -2525 influences corticosteroid-mediated increase in vWF level and possibly hypercoagulability of the blood. This study was undertaken to correlate plasma vWF levels with plasma cortisol and single nucleotide polymorphisms (SNPs) at positions -2659 and -2525 in Cushing syndrome patients in India. Samples from 22 endogenous...
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