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Article

Hypercortisolism and pregnancy upregulate von Willebrand factor through different mechanisms: report on a pregnant patient with Cushing's syndrome.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jul 2010

Casonato Alessandra, Daidone Viviana, Pontara Elena, Albiger Nora, Cattini Maria G, Scaroni Carla

Abstract excerpt

Von Willebrand factor (VWF) is reportedly increased in pregnancy and Cushing's syndrome, inducing a hypercoagulable state. In Cushing's syndrome, VWF gene promoter polymorphisms modulate cortisol-dependent VWF upregulation, haplotype 1 (GCAG) and short GT-repeats (GT)(S) being the susceptible, an...

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Share to Cushing Syndrome
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Share to Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Pregnancy Complications

Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 20614575
DOI: 10.1097/mbc.0b013e328338dbba

Genes

VWF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20614575-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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