Article
Selection of hepatitis B virus (HBV) vaccine escape mutants in HBV-infected and HBV/HIV-coinfected patients failing antiretroviral drugs with anti-HBV activity.
Journal of acquired immune deficiency syndromes (1999) - 1 Nov 2007
Sheldon Julie, Ramos Belen, Garcia-Samaniego Javier, Rios Pilar, Bartholomeusz Angeline, Romero Miriam, Locarnini Stephen, Zoulim Fabien, Soriano Vincent
Abstract excerpt
BACKGROUND: Given the overlap between envelope and polymerase in the hepatitis B virus (HBV) genome, changes in antigenic sites of the HBV surface antigen may occur as a result of selection of drug-resistance mutations. METHODS: Serum HBV-DNA was isolated from 71 patients with chronic hepatitis B...
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