Article
Interleukin-6 is not essential for bone turnover in hypothyroid mice.
Folia histochemica et cytobiologica - 1 Jan 2007
Mysliwiec Janusz, Zbucki Robert, Winnicka Maria, Sawicki Boguslaw, Nikolajuk Agnieszkar, Kaminski Karol, Mysliwiec Piotr, Musial Wlodzimierz, Bondyra Zofia, Walecki Jerzy, Gorska Maria
Abstract excerpt
Interleukin-6 (IL-6) has been shown to be involved in the pathogenesis of several bone diseases characterized by an imbalance between bone resorption and formation. The aim of the study was to estimate serum markers of bone turnover: osteoclast-derived tartrate-resistant acid phosphatase form 5a (TRACP 5b) and osteocalcin in IL-6-deficient mice to assess the role of IL-6 in bone metabolism in hypothyroidism in...
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