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Article

Regional differences in chondrocyte metabolism in osteoarthritis: a detailed analysis by laser capture microdissection.

Arthritis and rheumatism - 1 Jan 2008

Fukui Naoshi, Ikeda Yasuko, Ohnuki Toshiyuki, Tanaka Nobuho, Hikita Atsuhiko, Mitomi Hiroyuki, Mori Toshihito, Juji Takuo, Katsuragawa Yozo, Yamamoto Seizo, Sawabe Motoji, Yamane Shoji, Suzuki Ryuji, Sandell Linda J, Ochi Takahiro

Abstract excerpt

OBJECTIVE: To determine the change in metabolic activity of chondrocytes in osteoarthritic (OA) cartilage, considering regional difference and degree of cartilage degeneration. METHODS: OA cartilage was obtained from knee joints with end-stage OA, at both macroscopically intact areas and areas with various degrees of cartilage degeneration. Control cartilage was obtained from age-matched donors. Using laser...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 18163492
DOI: 10.1002/art.23175

Genes

SOX5
SOX6
SOX9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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