Article
Study on GRIA2, GRIA3 and GRIA4 genes highlights a positive association between schizophrenia and GRIA3 in female patients.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Sept 2008
Magri Chiara, Gardella Rita, Valsecchi Paolo, Barlati Stefano Davide, Guizzetti Luca, Imperadori Laura, Bonvicini Cristian, Tura Gian Battista, Gennarelli Massimo, Sacchetti Emilio, Barlati Sergio
Abstract excerpt
Impairment of glutamatergic neurotransmission is one of the major hypotheses proposed to explain the neurobiology of schizophrenia. Therefore, the genes involved in the glutamate neurotransmitter system could be considered potential candidate genes for schizophrenia susceptibility. A systematic study on alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptor genes has been carried out and the...
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