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Article

Association of a GRIA3 gene polymorphism with migraine in an Australian case-control cohort.

Headache - 1 Sept 2013

Maher Bridget H, Lea Rod A, Follett Jordan, Cox Hannah C, Fernandez Francesca, Esposito Teresa, Gianfrancesco Fernando, Haupt Larisa M, Griffiths Lyn R

Abstract excerpt

BACKGROUND: The excitatory neurotransmitter glutamate has been implicated in both the hyperexcitability required for cortical spreading depression as well as activation of the trigeminovascular system required for the allodynia associated with migraine. Polymorphisms in the glutamate receptor ionotropic amino-3-hydroxy-5-methyl-4-isoxazole-propionin acid 1 (GRIA1) and GRIA3 genes that code for 2 of 4 subunits of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23772601
DOI: 10.1111/head.12151

Genes

GRIA3
GRIA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of a GRIA3 gene polymorphism with migraine in an Australian case-control cohort.PMID 23772601Read ↗

Case-control study of GRIA1 and GRIA3 gene variants in migraine.Semantic proximity Read ↗

Common variants in the regulative regions of GRIA1 and GRIA3 receptor genes are associated with migraine susceptibility.Semantic proximity Read ↗

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Study on GRIA2, GRIA3 and GRIA4 genes highlights a positive association between schizophrenia and GRIA3 in female patients.Semantic proximity Read ↗

Identification of Polymorphisms in EAAT1 Glutamate Transporter Gene SLC1A3 Associated with Reduced Migraine Risk.Semantic proximity Read ↗

Reclassification of the GRIA3 splice-site variant in an X-linked family with intellectual disability and psychiatric symptomsSemantic proximity Read ↗

Exomic sequencing of the ionotropic glutamate receptor N-methyl-D-aspartate 3A gene (GRIN3A) reveals no association with schizophrenia.Semantic proximity Read ↗

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