Article
Axoneme specialization embedded in a "generalist" beta-tubulin.
Cell motility and the cytoskeleton - 1 Mar 2008
Popodi Ellen M, Hoyle Henry D, Turner F Rudolf, Xu Ke, Kruse Spencer, Raff Elizabeth C
Abstract excerpt
The relationship between the primary structure of the beta-tubulin C-terminal tail (CTT) and axoneme structure and function is explored using the spermatogenesis-specific beta2-tubulin of Drosophila. We previously showed that all beta-tubulins used for motile 9 + 2 axonemes contain a conserved sequence motif in the proximal part of the CTT, the beta-tubulin axoneme motif. The differential ability of tubulin...
Topics
- Amino Acid Sequence
- Animals
- Axoneme
- Dimerization
- Drosophila melanogaster
- Fertility
- Male
- Mitosis
- Molecular Sequence Data
- Mutant Proteins
- Mutation
- Protein Processing, Post-Translational
