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Article

Induction of CYP1A2 by heavy coffee consumption in Serbs and Swedes.

European journal of clinical pharmacology - 1 Apr 2008

Djordjevic Natasa, Ghotbi Roza, Bertilsson Leif, Jankovic Slobodan, Aklillu Eleni

Abstract excerpt

OBJECTIVES: To investigate the influence of coffee consumption on CYP1A2 enzyme activity controlling for the effects of smoking and oral contraceptive (OC) use among Serbs and Swedes and to compare CYP1A2 activity between the two populations. METHODS: Data on oral contraceptive use, habitual coffee consumption and smoking habits were obtained from 100 Serbian and 149 Swedish healthy volunteers using a detailed...

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PMID: 18157525
DOI: 10.1007/s00228-007-0438-6

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