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Article

Calcium homeostasis and mitochondrial dysfunction in striatal neurons of Huntington disease.

The Journal of biological chemistry - 29 Feb 2008

Lim Dmitry, Fedrizzi Laura, Tartari Marzia, Zuccato Chiara, Cattaneo Elena, Brini Marisa, Carafoli Ernesto

Abstract excerpt

Dysfunctions of Ca2+ homeostasis and of mitochondria have been studied in immortalized striatal cells from a commonly used Huntington disease mouse model. Transcriptional changes in the components of the phosphatidylinositol cycle and in the receptors for myo-inositol trisphosphate-linked agonists have been found in the cells and in the striatum of the parent Huntington disease mouse. The overall result of the...

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PMID: 18156184
DOI: 10.1074/jbc.M704704200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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