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Article

Retinoic acid causes abnormal development and segmental patterning of the anterior hindbrain in Xenopus embryos.

Development (Cambridge, England) - 1 Dec 1991

Papalopulu N, Clarke J D, Bradley L, Wilkinson D, Krumlauf R, Holder N

Abstract excerpt

Retinoic acid is a very potent teratogen and has also been implicated as an endogenous developmental signalling molecule in vertebrate embryos. One of the regions of the embryo reliably affected by exogenously applied RA is the hindbrain. In this paper, we describe in detail the hindbrain of Xenopus laevis embryos briefly treated with various levels of RA at gastrula stages. Such treatments lead to development of...

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Identifiers

PMID: 1811933
DOI: 10.1242/dev.113.4.1145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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