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Article

Craniofacial variability and morphological integration in mice susceptible to cleft lip and palate.

Journal of anatomy - 1 Dec 2004

Hallgrímsson Benedikt, Dorval Curtis J, Zelditch Miriam Leah, German Rebecca Z

Abstract excerpt

A/WySnJ mice are an inbred strain that develops cleft lip with or without cleft palate (CL/P) with a frequency of 25-30% and a predominantly unilateral expression pattern. As in humans, the pattern of incomplete penetrance, and variable and frequent unilateral expression suggests a role for altered regulation of variability (developmental stability, canalization and developmental integration) during growth. We...

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Identifiers

PMID: 15610397
DOI: 10.1111/j.0021-8782.2004.00356.x
PMCID: PMC1571426

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