Article
Association of the Pro12Ala polymorphism in the PPAR-gamma2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study.
Diabetes - 1 Aug 2002
Lindi Virpi I, Uusitupa Matti I J, Lindström Jaana, Louheranta Anne, Eriksson Johan G, Valle Timo T, Hämäläinen Helena, Ilanne-Parikka Pirjo, Keinänen-Kiukaanniemi Sirkka, Laakso Markku, Tuomilehto Jaakko
Abstract excerpt
The association of the Pro12Ala polymorphism of the PPAR-gamma2 gene with the incidence of type 2 diabetes was investigated in 522 subjects with impaired glucose tolerance (IGT) participating in the Finnish Diabetes Prevention Study. Subjects were randomized to either an intensive diet and exercise group or a control group. By 3 years of intervention, the odds ratio of the development of type 2 diabetes for...
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