Article
Resistance of Porphyromonas gingivalis ATCC 33277 to direct killing by antimicrobial peptides is protease independent.
Antimicrobial agents and chemotherapy - 1 Feb 2008
Bachrach Gilad, Altman Hamutal, Kolenbrander Paul E, Chalmers Natalia I, Gabai-Gutner Michal, Mor Amram, Friedman Michael, Steinberg Doron
Abstract excerpt
Antimicrobial peptides are short, positively charged, amphipathic peptides that possess a wide spectrum of antimicrobial activity and have an important role in the host's innate immunity. Lack of, or dysfunctions in, antimicrobial peptides have been correlated with infectious diseases, including periodontitis. Porphyromonas gingivalis, a gram-negative anaerobe and a major pathogen associated with periodontal...
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