Article
A genome-wide analysis of LPS tolerance in macrophages.
Immunobiology - 1 Jan 2007
Mages Jörg, Dietrich Harald, Lang Roland
Abstract excerpt
Among the multiple mechanisms that control the intensity and duration of macrophage activation, the development of a state of refractoriness to a second stimulation in cells treated with lipopolysaccharide (LPS) has long been recognized. Release of inhibitory cytokines and alterations in intracellular signaling pathways may be involved in the development of LPS tolerance. Although a number of molecules have been...
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