Article
Apoptosis: a potential triggering mechanism of neurological manifestation in <i>Plasmodium falciparum </i>malaria
1 Nov 2007
Abstract excerpt
Plasmodium falciparum infection can lead to a life threatening disease and the pathogenetic mechanisms of severe manifestations are not fully understood. Here, we investigated the capacity of P. falciparum-parasitized red blood cells (PRBC) from 45 children with clinical malaria to induce endothelial cell (EC) apoptosis. In all subjects, PRBC that cytoadhered to ECs could be found albeit to a variable degree. By...
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