Article
Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms.
Nature cell biology - 1 Jan 2008
Corbit Kevin C, Shyer Amy E, Dowdle William E, Gaulden Julie, Singla Veena, Chen Miao-Hsueh, Chuang Pao-Tien, Reiter Jeremy F
Abstract excerpt
Primary cilia are microtubule-based organelles involved in signal transduction and project from the surface of most vertebrate cells. Proteins that can localize to the cilium, for example, Inversin and Bardet-Biedl syndrome (BBS) proteins, are implicated in both beta-catenin-dependent and -indepe...
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