Article
An unexpected outcome of surface engineering an integral membrane protein: improved crystallization of cytochrome ba(3) from Thermus thermophilus.
Acta crystallographica. Section F, Structural biology and crystallization communications - 1 Dec 2007
Liu Bin, Luna V Mitch, Chen Ying, Stout C David, Fee James A
Abstract excerpt
Past work has shown that it is feasible to mutate surface residues of soluble proteins and to a lesser extent membrane proteins in order to improve their crystallization behavior. Described here is a successful application of this approach to the integral membrane protein Thermus thermophilus cyt...
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