Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A first stage genome-wide screen for regions shared identical-by-descent in Hutterite families with multiple sclerosis.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jun 2008

Dyment David Alexandre, Cader M Zameel, Datta Anita, Broxholme S John, Cherny Stacey S, Willer Cristen J, Ramagopalan Sreeram, Herrera Blanca M, Orton Sarah, Chao Michael, Sadovnick A Dessa, Hader Mary, Hader Walter, Ebers George C

Abstract excerpt

The complexity of multiple sclerosis (MS) genetics has made the search for novel genes using traditional sharing methods problematic. In order to minimize the genetic heterogeneity present in the MS population we have screened the Canadian MS population for individuals belonging to the Hutterite Brethren. Seven Hutterites with clinically definite MS were ascertained and are related to a common founder by eight...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Canada
Share to Family Health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Founder Effect

Share to Genes, MHC Class II

Share to Genome, Human

Share to HLA-DR Antigens

Share to HLA-DRB1 Chains

Share to Multiple Sclerosis

Source

Identifiers

PMID: 18081025
DOI: 10.1002/ajmg.b.30620

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A first stage genome-wide screen for regions shared identical-by-descent in Hutterite families with multiple sclerosis.PMID 18081025Read ↗

Genetic susceptibility to MS: a second stage analysis in Canadian MS families.Semantic proximity Read ↗

An extended genome scan in 442 Canadian multiple sclerosis-affected sibships: a report from the Canadian Collaborative Study Group.Semantic proximity Read ↗

Investigating the role of common and rare variants in multiplex multiple sclerosis families reveals an increased burden of common risk variation.Semantic proximity Read ↗

Mapping candidate non-MHC susceptibility regions to multiple sclerosis.Semantic proximity Read ↗

Genetic susceptibility to multiple sclerosis in African Americans.Semantic proximity Read ↗

Sharing of a conserved haplotype suggests a susceptibility gene for multiple sclerosis at chromosome 17p11.Semantic proximity Read ↗

Refining the association of MHC with multiple sclerosis in African Americans.Semantic proximity Read ↗

A genome-wide screen for association in Hungarian multiple sclerosis.Semantic proximity Read ↗

SNP mapping and candidate gene sequencing in the class I region of the HLA complex: searching for multiple sclerosis susceptibility genes in Tasmanians.Semantic proximity Read ↗

Two genetic variants explain the association of European ancestry with multiple sclerosis risk in African-Americans.Semantic proximity Read ↗

Common and Low Frequency Variants in MERTK Are Independently Associated with Multiple Sclerosis Susceptibility with Discordant Association Dependent upon HLA-DRB1*15:01 Status.Semantic proximity Read ↗

PRKCA and multiple sclerosis: association in two independent populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.