Article
Serotonergic effects of smoking are independent from the human serotonin transporter gene promoter polymorphism: evidence from auditory cortical stimulus processing.
Pharmacopsychiatry - 1 Jul 2005
Gallinat J, Kunz D, Lang U E, Kalus P, Juckel G, Eggers J, Mahlberg R, Staedtgen M, Wernicke C, Rommelspacher H, Smolka M N
Abstract excerpt
BACKGROUND: Cigarette smoking has been associated with mood enhancing properties and modulating effects on serotonin activity. The loudness dependence (LD) of the auditory-evoked N1/P2-component has been related to serotonergic neurotransmission, i. e. the allelic variants in the promoter of the 5-hydroxytryptamine-transporter (5-HTT) gene (SCL6A4). Moreover, smoking behavior has been associated to the...
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