Article
Association of 5-HT1B receptor polymorphisms with the loudness dependence of auditory evoked potentials in a community-based sample of healthy volunteers.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jun 2008
Juckel Georg, Hegerl Ulrich, Giegling Ina, Mavrogiorgou Paraskevi, Wutzler Alexander, Schuhmacher Christiane, Uhl Idun, Brüne Martin, Mulert Christoph, Pogarell Oliver, Rujescu Dan
Abstract excerpt
The terminal autoreceptor 5-HT1B is centrally involved in the regulation of the brain serotonergic system and in several psychiatric disorders including depression, addiction, and obsessive-compulsive disorder. The loudness dependence of the auditory evoked N1/P2-component (LDAEP; primary auditory cortex) is currently considered as one of best-validated indicators of serotonergic neurotransmission, especially for...
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