Article
Role of APOBEC3G/F-mediated hypermutation in the control of human immunodeficiency virus type 1 in elite suppressors.
Journal of virology - 1 Mar 2008
Gandhi Shiv K, Siliciano Janet D, Bailey Justin R, Siliciano Robert F, Blankson Joel N
Abstract excerpt
While many studies show that the APOBEC3 family of cytidine deaminases can inhibit human immunodeficiency virus type 1 (HIV-1) replication, the clinical significance of this host defense mechanism is unclear. Elite suppressors are HIV-1-infected individuals who maintain viral loads below 50 copie...
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