Article
Elevated hypermutation levels in HIV-1 natural viral suppressors.
Virology - 1 Sept 2013
Eyzaguirre Lindsay M, Charurat Manhattan, Redfield Robert R, Blattner William A, Carr Jean K, Sajadi Mohammad M
Abstract excerpt
Mutations in the HIV-1 proviral genomes delay the progression of the disease. We compared the mutation status in full-length proviral genomes of 23 HIV-infected patients with undetectable viral loads in the absence of therapy named natural viral suppressors (NVS) or Elite Controllers with 23 HIV-infected controls (10 patients on HAART treatment and 13 untreated patients). Provirus DNA was extracted from PBMC for...
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