Complement deficiency and autoimmunity.

doi:10.1097/00008480-199810060-00011

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Article

Complement deficiency and autoimmunity.

Current opinion in pediatrics - 1 Dec 1998

Sullivan K E

Abstract excerpt

Complete deficiency of one of the early components (C1, C4, or C2) of the classical pathway of the complement cascade is one of the strongest genetic risk factors for systemic lupus erythematosus that has been recognized. The lupus that occurs in complement-deficient individuals typically present...

Topics

Antibody Formation
Antigen-Antibody Complex
Autoimmune Diseases
Child
Complement C1
Complement C2
Complement C4
Complement Pathway, Classical
Disease Models, Animal
Genetic Predisposition to Disease
Humans
Lupus Erythematosus, Systemic
Risk Factors

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