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Article

A protective role for innate immunity in systemic lupus erythematosus.

Nature reviews. Immunology - 1 Oct 2004

Carroll Michael C

Abstract excerpt

Clinical and genetic studies in humans and animal models indicate a crucial protective role for the complement system in systemic lupus erythematosus (SLE). This presents a paradox because the complement system is considered to be an important mediator of the inflammation that is observed in patients with SLE. One current view is that complement provides protection by facilitating the rapid removal of apoptotic...

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Identifiers

PMID: 15459673
DOI: 10.1038/nri1456

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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